Tom,I built the 2PI Towers as my first speaker project and had very little problems with it. The only trouble I had during the build was moving it on and off the workbench. I used 1" MDF and over-braced, so it became pretty heavy.
I did have all the panels cut to spec at the big-box store, so that helped a lot. When I got home, it was just a matter of piecing them together. Most big-box stores that I know of will cut for you if you give them a cutting diagram.
Gar.