I checked out the Z-2300 system on the Logitech website. I assume that your computer will be in the center of the desk and you will be watching/listening from either the chair or the sofa. You did not specify what is in the corner between your desk and the bed. My opinions are: 1. the satellite speakers are even shown without their cloth covers on the website so removing them should be OK. At most it might make a tiny difference to the highs (make them slightly louder). I would worry more that you might be exposing them to cone damage (e.g.)from spilled coffee, etc. 2. the woofer location under the desk should not be optimal, especialy with such small satellites the crossover with the woofer is probably fairly high in frequency and mid frequencies bouncing around down there are not a good thing for good sound. Better would be a room corner such as between the bed and desk - either on the floor or elevated up the wall corner. Another possibility would be over the computer on the wall if there was a shelf, perhaps. Trial and error are called for here. The rule you read is often a good start, but it is intended for much larger rooms than you have here. In the end it is your own ears that will have to judge when playing music that you like best. You have good equipment. Good luck! -Dick