doucanoe- G'day, Spectrum77 here.
Glad you're taking the plunge- you won't regret it.
From my experience using 4 Pi derivative bass bins (JBL 4607?) with 2226H and the 7 Pi mid and high horns I'd say if you've no other option due to lack of corners in your room... go for it. However, there is a difference in mid reproduction, of course. If possible, can you construct 'false' wall(s) to form corners?