The JBL 2220's don't look like they'll go down real low, but then again, JBL 2205's don't go down just real low either, yet bass sounds very powerful in seven π's with 2205's. So naturally, I'd put your 2220's in a seven π cornerhorn configuration, tuned for the 2220, of course. I expect they'll probably work very well in ten π's too, and in that case, I'd use the same cabinet that is recommended for the JBL 2226.For a seven π cornerhorn, you'll want to make the motor cabinet 2ft3 tuned to 80Hz. A 5.5" diameter hole cut through a 3/4" baffle will tune it nicely. But since you also have 2240's, you might build subwoofers from them, and then just put the 2220's in sealed or bass-reflex cabinets for midbass duty. I'd probably still go with PiAlign recommendations, and use a 2ft3 tuned to 80Hz for the 2220's. I'd probably run an EBS alignment and use the same subwoofer cabinet as I normally recommend for other JBL 224x 18" woofers. So I'd say put the 2240's in an 8-10ft3 cabinet tuned to 30-35Hz.
The PSD2002's will do nicely for tweeters, but if the 2220's are like the 2205's, you'll need a midrange subsystem. I think JBL is still selling 2123's, so that would work out just great.