I use a commercial style hot melt gun for building crossover boards and holding down the components. Takes the 12" sticks. I dont see any point to the Franklin system unless you need some kind of weather resistant or water proof glueing system. Yellow glue holds hardwoods and plywood stronger than at the joint than the wood itself.
MDF is only paper and you only have about .020 worth of bond and the paper breaks.
I'm saying if the joint you get with the glue is stronger than the material and it's compatible to withstand the environment (your living room) Then the simple glue's are good enough.
The one thin that could be exciting would be an "instant" bond. How much product is lost or wasted in the mixing tube of some of these systems could be a problem if you only need to apply a little every now and then
Bill
Bill